Isoleucine Promotes Fat Loss

Isoleucine Promotes Fat Loss

Japanese researchers from Oita University found that IL supplements prevented weight gain and fat accumulation in mice fed a high-fat diet (45 percent of caloric intake). IL decreased gut fat by 49 percent, compared to a placebo. IL reduced muscle and liver fat and prevented increases in blood insulin. IL also increased the activity of uncoupling proteins in muscle cells, which increased fat burning. Supplementing isoleucine might be a simple way to cut appetite, speed metabolic rate, and lose body fat. (Journal Nutrition, 140: 496-500, 2010)