Testosterone Makes You Quick Draw McGraw? The physiological sexual excitation is mediated both by the sympathetic and the parasympathetic nervous system. Most studies show a serotonergic (ejaculatory) involvement in premature ejaculation (PE).There is definitive medical and scientific evidence referenced by The National Library Of Medicine, that elevated levels of dopamine can have a profound negative impact on ejaculatory control in men and show that drugs which stimulate dopamine receptors can actually cause premature ejaculation. As early as 1972, it was reported in Life Science Journal "that dopamine is the central mediator of emission of seminal fluid in male rats". Furthermore, the medical literature that links elevated dopamine neurotransmission with aggravating existing premature ejaculation or even causing early ejaculation in men who otherwise had no difficulties with maintaining ejaculatory control. Testosterone increases dopamine; researchers from Italy examined the role of role of testosterone in relation to timing of ejaculation. Researchers examined the relationship between testosterone and premature ejaculation (PE) or delayed ejaculation (DE) to those without ejaculatory dysfunction. 2,437 male patients with sexual dysfunction was studied. Among the patients studied, 714 men had PE and 121 had DE. In the youngest age group (25-40 years), subjects with PE reported higher TT and free testosterone (FT) levels when compared to the other groups (subjects with DE or those without PE and DE). Conversely, in the oldest age group (55-70 years), lower TT and FT levels were observed in DE subjects. The researchers hypothesized that testosterone has a enhancement of dopamine which causes ejaculation.

Corona G, Jannini EA, Mannucci E, Fisher AD, Lotti F, Petrone L, Balercia G, Bandini E, Chiarini V, Forti G, Maggi M. Different Testosterone Levels Are Associated with Ejaculatory Dysfunction. J Sex Med. 2007 Apr 9;