Sports Supplement Review
By Robbie Durand, M.A.
RIPPED FREAK™: The World's First Hybrid Fat Burner
It's easy to get lost when buying a fat burner. The market is filled with dozens of fat burners that have the same ingredients, just with a different bottle and label. If you are looking for a fat burner that stimulates thermogenesis through an entirely new mechanism, check out PharmaFreak Technologies' Ripped Freak™.
What makes Ripped Freak™ different from other fat burners? Well, Ripped Freak™ is the first hybrid supplement that bridges the gap between nature and pharmaceuticals! There are some very unique ingredients that make Ripped Freak™ different from all the other fat burners on the market. For instance, new EGCG derivatives, 1,3-D™ (from geranium oil extract), and a unique pepper extract called CH-19 sweet red pepper.
On top of that, Ripped Freak™ also uses the methyl gallate ester combined with caffeine and raspberry ketone to deliver more powerful energizing and fat-burning effects! The methyl gallate ester is used as an intermediate in the pharmaceutical industry and it's attached to drugs in order to provide superior bioavailability and an extended half-life in the body, and that's exactly why it's being used in the Ripped FreakTM formula!
There's one other thing that makes Ripped FreakTM different from all the other fat burners on the market. Unlike many other fat burners, Ripped Freak™ doesn't include tiny amounts of several ingredients in the formula. Instead, the makers of Ripped Freak™ have critically selected a group of key, powerful ingredients, and have included them in very high doses, so they can truly have a significant impact on fat loss. In fact, the Ripped FreakTM formula has been clinically found to increase norepinephrine by up to 112 percent and epinephrine by up to 300 percent. The Ripped FreakTM formula attacks every weight loss mechanism in the body. Ripped FreakTM turns on the gas pedal for fat metabolism and rapid fat loss.
The Science of Fat Metabolism
Ripped FreakTM activates large increases in catecholamines. The physiological role of the sympathetic nervous system is a major target of study for loss of bodyweight and fat loss. The principal role players in the sympathetic nervous system are hormones called catecholamines and the adrenergic receptors (adrenoceptors) upon which they act.
The catecholamines are the primary regulators of fat breakdown in cells by way of stimulation of adrenoceptors on the fat cell membrane. The activation of the sympathetic nervous system is involved in diet-induced thermogenesis, exercise, and Ripped FreakTM.
In humans, catecholamines are potent activators of fat lipolysis, the breakdown of triglycerides from adipose tissue into glycerol and free fatty acids. Triglycerides are the stored form of fat used in energy metabolism. Fat cells are located in subcutaneous adipose tissue (under the skin), in the abdominal cavity surrounding organs (visceral fat), and in between the cells of muscle and other tissues (intracellular lipids).
Catecholamines (epinephrine and norepinephrine) are powerful stimulators of triglycerides from adipose tissue and exert their effects by binding to beta-adrenergic receptors (beta1, beta2, and beta3 receptors), stimulating fat oxidation; additionally catecholamines prevent fat cell formation by blocking the actions of alpha2 adrenoreceptors on white adipose cells.5 Several ingredients found in the Ripped Freak™ formula, including EGCG, caffeine-methyl gallate ester, raspberry ketone, 1,3-D™ and CH-19 Sweet Red Pepper extract help dramatically enhance the complex processes involved in fat metabolism, and as a result, induce maximum fat loss.
The Research Behind EGCG and Fat Loss
Epigallocatechin-3-Gallate or EGCG, the most abundant catechin in green tea, representing approximately 35 percent of total catechins, has received the most attention as a potential anti-obesigenic agent. Studies suggest that ECGC favorably affects bodyweight and body fat. Long-term treatment (12 weeks) with green tea extract containing 115 mg EGCG daily significantly reduced body fat (7 percent), bodyweight (2 percent), and BMI (2 percent) in men and women.1
These findings are supported by other studies in which healthy volunteers received a green tea extract containing 270-300 mg EGCG, and reduced bodyweight by 1.2 percent to 1.5 percent. 2,3 ECGC seems to be especially effective in reducing body fat around the abdomen. In one study, total body fat was reduced by 6.5 percent, mainly due to a reduction of visceral fat (8.7 percent).3
Burning fat is a complex process that involves several mechanisms, which include: 1) decreasing digestive activity, 2) increasing lipolytic activity, 3) decreasing lipogenic activity, 4) increasing fat oxidation and thermogenesis, 5) modulation of the activity and expression of lipoprotein lipase (fat storage enzyme), 6) decreasing the cell number and size of adipocytes.
Amazingly, a large body of evidence from studies suggests that all these activities can be positively affected by green tea extracts or EGCG.4 The scientists at PharmaFreakTechnologies are using the latest research on green tea extract to stimulate catecholamines for fat burning. The RIPPED FREAK™ formula contains five newly-discovered methylated derivatives of (-)-epigallocatechin-3-O-gallate (EGCG) from green tea extract, and as already explained, the methyl groups increase the lipophilicity and absorption into target cells, making the five EGCG derivatives found in RIPPED FREAK™ superior to some forms of EGCG found in other fat burners.
Methyl Gallate Ester: The Key to Maximum Bioavailability
When combined with established fat-burning ingredients, the methyl gallate ester provides several key advantages! The methyl gallate ester is used in the pharmaceutical industry to provide superior bioavailability and an extended half-life in the body. This means that by combining the methyl gallate ester with key fat-loss ingredients, RIPPED FREAK™ has a greater ability to penetrate fat cell membranes. In sum, the methyl gallate ester will increase the absorption of ingredients into target cells, resulting in greater fat-loss effects!
The methyl gallate ester also increases the bioavailability of ingredients through another distinct mechanism. It has the ability to inhibit the enzymes responsible for ingredient biotransformation in the gut. Since the methyl gallate ester inhibits degradation of ingredients in the gut, they can be more effectively absorbed and distributed throughout the body to their target tissues. This means more powerful effects and a greater impact on total fat-burning capacity. RIPPED FREAK™ combines the methyl gallate ester with clinically-proven fat-fighting ingredients such as caffeine and raspberry ketone, to take advantage of its positive effects on bioavailability and extended release in the body.
CH-19 Sweet Red Pepper Extract
CH-19 sweet red pepper extract is another unique and powerful ingredient in the Ripped Freak™ formula. It's nothing like any of the pepper or capsaicin extracts found in other fat burners on the market. The CH-19 sweet red pepper extract in Ripped Freak™ contains three isolated compounds that affect fat loss through multiple mechanisms.
First off, the compounds isolated from CH-19 sweet red pepper are clinically shown to increase core body temperature by stimulating the vanilloid receptors. This induces heat loss and heat production at the same time and dissipates food as energy, resulting in enhanced lipolysis and reduced lipogenesis. As a matter of fact, this is the exact same way that the old bodybuilding drug DNP (2,4-Dinitrophenol) works, except unlike DNP, CH-19 sweet red pepper is safe to consume!
The research on CH-19 sweet red pepper also shows that it has the ability to increase oxygen consumption, increase uncoupling protein 1 and 2 (UCP1 and UCP2), increase gene transcription of UCP2 mRNA in adipose (fat) tissue and increase epinephrine (adrenaline). All of these effects have a huge impact on fat loss and that's why a mega dose of CH-19 sweet is included in the Ripped Freak™ formula.
1,3-D™ from Geranium Oil
Another really innovative ingredient found in Ripped Freak™ is 1,3-D™, which is isolated from geranium oil. 1,3-D™ resembles the body's own chemical messenger, epinephrine (adrenaline), and works through a similar chemical pathway as ephedrine, causing a rise in cAMP, the chemical messenger that triggers fat release. 1,3-D™ is a powerful central nervous system stimulant, which is especially valuable to athletes when a high level of focus is needed. That's why many bodybuilders love to take Ripped Freak™ pre-workout. Not only does it help maximize fat loss, but it can also crank up your energy, strength and endurance!
Don't Be Fooled by Imitation Products!
Don't be fooled into thinking that supplements like regular old caffeine and green tea are just as effective at burning fat as an innovative product like Ripped Freak™, or you are going to be sadly disappointed. RIPPED FREAK™ is the only product on the market that contains the methyl gallate ester, 1,3-D™ and very high dosages of other ingredients— don't be fooled by cheap imitations or knock-offs! After just one dose, you'll quickly begin to realize just how powerful Ripped Freak™ really is.
For more information, please go to: http://www.rippedfreak.com/
References:
1. Tsuchida T, Itakura H, Nakamura H: Reduction of body fat in humans by long-term ingestion of catechins. Prog Med, 22 :2189-2203,2002 .
2. Nagao T, Komine Y, Soga S, Meguro S, Hase T, Tanaka Y, Tokimitsu I: Ingestion of a tea rich in catechins leads to a reduction in body fat and malondialdehyde-modified LDL in men. Am J Clin Nutr, 81 :122.
3. Hase, T.K., Y., Meguro, S., Takeda, Y., Takahashi, H., et al.: Anti-obesity effects of tea catechins in humans. J Oleo Sci, 50 :599-605,2001 .
4. Kao YH, Chang HH, Lee MJ, Chen CL: Tea, obesity, and diabetes. Mol Nutr Food Res, 50 :188-210,2006 .
5. Lafontan M, Berlan M. Fat cell adrenergic receptors and the control of white and brown fat cell function. J Lipid Res, 1993 Jul;34(7):1057-91. Review.