Mediator^® Phosphatidic Acid (PA)

Anabolic Pathway to Muscle Growth

Mediator^®Phosphatidic Acid (PA), when orally ingested, provided noticeable effects of adding muscle mass, increasing strength and reducing fat mass.

A giant, gleaming skyscraper that towers above a city street didn’t build itself – and neither can your ideal body. You know that you need a lot of protein to build the muscle you want, but that protein needs some help. The amino acids in protein are just the raw materials – you need strong, healthy workers to put those building blocks to good use. Phosphatidic acid (PA) is the ultra-fit workforce you need to build muscle mass and strength, but your body has a limited capacity to produce PA on its own. You already supplement your protein intake, so why not supplement your PA as well – and that’s where Mediator^® Phosphatidic Acid (PA) from Chemi Nutra comes in. Mediator^® PA is supported by numerous studies that consistently demonstrate that it profoundly impacts muscle mass and strength – and impacts loss of fat mass.

Mediator^® Phosphatidic Acid, in combination with exercise, amino acids and other factors combine as an anabolic pathway leading to muscle hypertrophy and strength increases. When Mediator^® PA is accompanied by your usual workout and protein shake, you will be single-handedly accelerating muscular growth in an easy, convenient way.

Accelerate Muscle Protein Synthesis

Mediator^® Phosphatidic Acid is a lipid messenger that accelerates muscle protein synthesis through the Mammalian Target of Rapamycin (mTOR) pathway. Phosphatidic acid activates mTOR signaling, and this turns on and manages critical muscle protein synthesis (MPS). MPS takes the available amino acids from ingested proteins from meals, and via translation uses them as genetic templates to reassemble from them new striated muscle. But without enough PA, there’s not enough mTOR activation to build the muscle you hope for. Enter Mediator^® Phosphatidic Acid (PA) – a key component of your anabolic pathway to muscle growth.

When ingested and followed with muscular exercise and protein intake, Mediator^®, Chemi Nutra’s branded Phosphatidic Acid (PA) dietary ingredient, dramatically activates the protein synthesis-regulating mTOR pathway. By activating the body’s mTOR pathway, Mediator^® Phosphatidic Acid can help individuals gain both lean muscle mass and strength, especially when accompanied with weight bearing or cardio exercise, and adequate protein intake. And Mediator^® Phosphatidic Acid has been proven safe and effective for fast muscle and strength building.

Added Muscle Mass

Following extensive investigation into the role of PA, Chemi Nutra discovered that exogenous PA could significantly influence load-induced growth of skeletal muscle via the mTOR signaling pathway. Chemi Nutra subsequently made substantial investment in several well-designed human and animal research studies to understand how PA can benefit individuals.

It was discovered that Mediator^® Phosphatidic Acid (PA), when orally ingested, provided noticeable effects of adding muscle mass, increasing strength and reducing fat mass, when adequate amounts of protein were administered within the anabolic window, to exercising individuals. As a result of these discoveries, the company was granted U.S. Patent No. 10,869,843 for its branded PA, which will have major significance in areas including sports nutrition and healthy aging.

Safe and Effective

Chemi Nutra has conducted a vast amount of research validating PA as safe and efficacious. Chemi Nutra has supported four efficacy trials and conducted five safety studies (acute toxicity study, 14-day toxicity study, 28-day toxicity study, reverse bacterial mutation test [Ames Test] and 90-day toxicity study) that demonstrate the safety of its novel, proprietary, PA ingredient compound.

Reach Your Goals With Mediator^® PA

Numbers talk: Try Chemi Nutra’s Mediator^® PA to get you or your clients over the last hurdle that might be in the way of reaching training or fitness goals. When taken as directed, Chemi Nutra’s branded, patented Mediator^® PA ingredient compound was demonstrated¹ to provide:

• Doubled Muscle Mass Gain

• Increased Strength

• Doubled Fat Mass Loss

Another study² showed that subjects who took PA experienced:

• 12.7% Increase of Squat Strength

• 2.6% Increase in Lean Body Mass (LBM)

Whereas placebo-treated subjects only saw:

• 9.3% improvement in squat strength

• 0.1% change in LBM

For more information, visit cheminutra.com

References:

1. Jordan M Joy, David M Gundermann, et al. Phosphatidic acid enhances mTOR signaling and resistance exercise induced hypertrophy. Nutrition & Metabolism volume 11, Article number: 29 (2014)

2. Jay R Hoffman, Jeffrey R Stout, et al. Efficacy of phosphatidic acid ingestion on lean body mass, muscle thickness and strength gains in resistance-trained men. Journal of the International Society of Sports Nutrition volume 9, Article number: 47 (2012)

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